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Institute of Nano Biomedical Engineering

Institute of nano biomedicine and engineering, Shanghai Jiao Tong University, which is directly the Key Laboratory of the Ministry of education for thin film and microtechnology, is one of the research institutes focused on the construction of micro Na science and technology, Shanghai Jiao Tong University. The Institute is led by Professor dahxiang Cui, the chief scientist of the nano973 project, and consists of a group of specially appointed professors and guest professors with experience in learning and working abroad, who are mainly engaged in the field of the intersection of nanomaterials and life science, medicine, exploring life phenomena and occurrence mechanisms at the nanoscale, and establishing new theories; Exploring the effects of nanomaterials, including metal nanoparticles (magnetic nanoparticles, quantum dots, upconversion nanoparticles, gold nanoparticles, etc.), biodegradable polymeric materials, etc., on human cells, health, environment, etc., focusing on studying the physical, chemical characteristics and biological effects of nanomaterials at the molecular level, cellular level, animal and human levels, and population and environmental level; Special attention is paid to the biocompatibility and biosafety studies of nanomaterials, focusing on the scientific issues such as agglomeration, transmembrane transport, crossing the blood-brain barrier, effects on immune cells, and biocompatibility that occur when nanomaterials interact with cells, etc.

While exploring the scientific questions, we carry out the marker screening and identification of gastric cancer, actively utilize nanomaterials and nanoeffects to enhance the sensitivity and specificity of marker detection such as tumor, combine microfluidic technology with chip technology, develop a new generation of nanodetection technology and equipment, develop a new generation of nanodrug delivery system, design and prepare multifunctional molecular imaging nanoprobes, To explore their applications in the translation of clinical medicine and solve key scientific problems in clinical diagnosis and treatment, so as to establish a foundation for clinical applications.

Our institute has cell and molecular biology laboratory, chemical synthesis and characterization laboratory, gene and protein engineering laboratory, cell culture laboratory, chip detection laboratory, molecular imaging laboratory, it can also share the well equipped State Key Laboratory of micro / nano fabrication, film and microtechnology key experiments of the Ministry of education and the full experimental equipment of analysis and testing center of Shanghai Jiao Tong University.

Research directions

Controllable preparation, characterization and applications of nanomaterials

Nanomaterials preparation, modification, self-assembly (including quantum dots, superparamagnetic nanospheres, colloidal gold and gold nanorods, dendritic molecules, carbon nanotubes and biodegradable materials, nucleic acid and protein materials with special functions) nanomaterials preparation, modification Self assembly (including preparation, separation, purification of nucleic acid and protein materials with special functionalities such as quantum dots, superparamagnetic nanospheres, colloidal gold and gold nanorods, dendritic molecules, carbon nanotubes and biodegradable materials)